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In diet-induced obese and ob/ob mouse models, SLU-PP-332 increased energy expenditure and fatty acid oxidation, and those changes were accompanied by decreased fat mass accumulation, with improvement in features of metabolic syndrome (a Journal of Pharmacology and Experimental Therapeutics study showing that the synthetic ERR agonist SLU-PP-332 alleviates metabolic syndrome in diet-induced obese and ob-ob mouse models)
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