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323 Their designs used the ATG16L1 binding peptide (ABP) and LC3 interacting region (LIR) from the autophagy receptors TMEM59 and SQSTM1
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While a three-wave design would have been ideal for testing mediation effects, practical constraints including school academic calendars, potential participant fatigue, and the risk of increased attrition led us to implement a two-wave approach
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