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“Amgen, the pharmaceutical company that produces Enbrel in the United States, still has patent protection over the drug, meaning other companies cannot yet make ‘biosimilar’ versions of the medication that tend to be less expensive.” There is no Enbrel biosimilar (comparable to a generic) yet

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As it is well known from heterogeneous catalysis, small particles are particularly reactive because of their high specific surface area and their high surface curvature that exposes many crystal faces and causes local defects [8,9,10,11,12]