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549 The reactive astrocytes can promote excitotoxic injury of motor neurons by producing nitric oxide and peroxynitrite, which cause mitochondrial damage and apoptosis in cultured neurons, decreasing glutamate transport, releasing pro-apoptotic mediators selectively toxic to motor neurons

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Researchers should check whether the COA is batch-specific, whether the compound name matches the listing, whether the method fields are clear, and whether the results are tied to the same lot