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Egg Aging: Mitochondria & Antioxidants Compared | TikTok
Mechanistically, impaired iron export—e.g., zinc-mediated inhibition of amyloid precursor protein (APP) ferroxidase activity—provides a route to local iron accumulation (Duce et al., 2010), while familial AD presenilin mutations confer selective vulnerability to ferroptosis in human neuronal models (Greenough et al., 2022)
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