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Furthermore, studies on animal models of chronic kidney disease (5/6 nephrectomy model) have demonstrated that curcumin, by increasing the expression of hepatic mitochondrial PGC-1α and PPARα proteins, not only reverses abnormal mitochondrial membrane potential but also ameliorates mitochondrial metabolic disorders by inhibiting hepatic lipogenesis [141]
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Any additional extreme modifications of diet are not usually required for HC patients who receive blood removal treatment
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