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In contrast, high-intensity exercise produces a more pronounced ROS surge which, if not properly regulated, can overwhelm the cell’s antioxidant capacity and lead to oxidative damage [160]
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GPX proteins and Parkinson’s disease An immunocytochemical study of GPX1 expression shows that dopaminergic neurons in the SNpc express low levels of this protein, while other regions not affected in PD, such the ventral tegmental area, express higher levels [108]
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