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Its advantages in overcoming drug resistance are: 1) Oral formulations are delivered through albumin binding or nanocarriers to avoid insufficient uptake caused by low hENT1 expression ( The NCI-MATCH subprogram (NCI-Molecular Analysis for Therapy Choice) is a large scale precision medicine clinical trial officially launched by the National Cancer Institute (NCI) in August 2015 (O'Dwyer et al., 2023)
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