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2.4.1 Other potential methods for overcoming anti CD38 mAbs resistance: the role of CD47 CD47, an integrin-associated receptor, is widely expressed on the surface of many cell types, including red blood cells and cancer cells (60)

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This links back to the overall health of the skin microbiome, and the amount of different types of bacteria on the skin affects how the whole skin community behaves, which plays a big role in whether the skin stays healthy or develops problems like acne