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Superoxide dismutase catalyzes the conversion of superoxide radicals into hydrogen peroxide, which is then broken down by catalase and GPx into water and oxygen, thereby preventing the accumulation of toxic byproducts and preserving the structural and functional integrity of sperm cells

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This epigenetic modification suppresses SLC7A11 transcription, thereby reducing xCT expression, impairing cystine uptake, and limiting intracellular GSH synthesis, ultimately heightening neuronal vulnerability to ferroptosis (92)