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Macrocytic/normocytic anaemia Neurological/neuropsychiatric symptoms: paresthesia, aphasia, ataxia, sensory loss, dementia, psychosis, paranoia, depression, mood swings, behavioural changes, etc Symptoms as glossitis, extreme fatigue, loss of appetite, see more Diabetes, Auto-immune thyroid disease, Crohn’s disease, MS, pancreatic insufficieny, gastric bypass, coeliac disease Use of medication : metformin, ppi’s, Questran, colchicine Vegan/strict vegetarian diet Further Information NICE Guideline on B12 deficiency in over 16's Guidelines on Cobalamin and Folate issued by the British Committee for Standards in Haematology Videos/documentaries about PA/B12 deficiency including from our Conferences on Pernicious Anaemia Presentation made at the Gastroenterology and Hepatology Conference Hooper M, Hudson P, Porter F, McCaddon A