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This imbalance in UC is characterized by a decrease in the overall proportions of the beneficial bacteria Bacteroides and Firmicutes and an increase in the overall proportions of potentially harmful bacterial groups, such as Actinobacteria and Proteobacteria

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For in vitro experiments, the cells were used at a concentration of 3.0×10 6 cells per well in 96-well plates in 100 µl of RPMI 1640 with 5% FCS