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In addition, Spirulina is reported to reduce neuroinflammation, prevent the onset of mental disorders, and improve glial cell activation in the brain parenchyma in conditions such as mood disorders, stress, and behavioral changes, as well as in diseases such as fibromyalgia (FM), which causes extensive musculoskeletal pain (103)

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While the daily dose was sufficient to maintain serum B12 levels above 156 pmol/l in almost all subjects, the weekly dose was only able to do so in 74% of subjects (Sanz-Cuesta, 2020)