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Inflammasome activation leads to the cleavage of pro-caspase-1 to generate active caspase-1 that cleaves gasdermin-D (GSDMD) to form membrane pores, which enables the release of cytokines, such as IL-1β
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In Arabidopsis, this PTM links the stress hormone ABA to Ca 2+ signaling via the regulation of annexin1 (AnnAt1), a protein which has protective effect against drought stress [290]
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