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Is uric acid a true antioxidant? Identification of uric acid oxidation products and their biological effects - PMC

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While ferroptosis helps eliminate infected or damaged cells, its dysregulation exacerbates inflammation, tissue injury, and alveolar-capillary barrier dysfunction in ARDS ( 2.2 Key molecular mechanisms of ferroptosis Ferroptosis is characterized by the iron-dependent accumulation of lipid peroxides, driven by dysregulated oxidative stress and impaired antioxidant defenses