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Feline Injection Site Sarcomas: Risk Factors, Diagnosis, Staging, and Treatment Algorithm | Today's Veterinary Practice
Chrousos et al
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Their function could be essential in a disease in which frataxin is deficient, since this protein has been proven to be involved in Fe-S cluster biogenesis [143] Therefore, correct Fe-S cluster biogenesis in mitochondria is intimately linked to cellular iron homeostasis, and failure in the assembly of mitochondrial Fe-S proteins upon frataxin deficiency results in increased iron import, availability and accumulation in mitochondria after the activation of IRP1 [68]
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