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Further analysis of single-cell RNA data revealed that PRMT1 was significantly upregulated in TEC clusters (Fig
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Macrophages stimulated by lipopolysaccharide (LPS) or interferon gamma (IFN-γ) polarize into M1 macrophages, characterized by increased expression of proinflammatory molecules such as IL-1β, IL-6, IL-8, tumor necrosis factor alpha (TNF-α) as well as inducible nitric oxide synthase (iNOS), which typically trigger Th1 T cell responses (Wuttge et al., 2001
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