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Peptides & Inflammation: Functional Medicine Approach (2026 Guide)
In addition, light also triggers ROS and Fe 2+ burst, lipid peroxidation, and decreased cell viability of RPE cell lines, resulting in retinal damage and degeneration by inducing ferroptosis via GSH-GPX4 and AIFM2-CoQ10-NADH systems (Li X
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Apart from these modes of action, riboflavin has also been shown to activate specific neuroactive molecules such as vitamin B 6 (which confers neuroprotection based on a role in serotonin production) 73 , homocysteine (which has a double-edged neurological role) 74 and kynurenine involved in glutamate excitotoxicity (i.e., excess of glutamate in neural synapse, resulting in death of neural cells) 75
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