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Other studies have shown that HIF-1α can promote the intercellular contact between FLS and T cells and B cells by up-regulating the expression of intercellular contact media and enhancing the secretion of inflammatory factors such as IL-6, IL-8, TNF-α, and IL-1β, thus exacerbating synovial inflammation (33–35)
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I'm using it alongside NAC and vitamin C and feel like the combination is doing something
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