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In certain embodiments, the oligonucleotide provided herein is a CpG oligonucleotide, comprising a modification including 5-halouridine or 5-alkynyluridine, or a truncated version thereof (e.g., those comprising a total of about 6 to about 16 nucleosides)
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One consequence of the lipid exchange between these two tissues is that also the circulating lipidome is changing: we observed an increase in both the unsaturation level and carbon chain length of lipids in the Drosophila hemolymph during starvation, a finding that aligns with those from the human studies 1
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