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5-Amino-1MQ works upstream of the scale. It inhibits NNMT, an enzyme highly active inside fat tissue that depletes NAD+ and drives adipocyte expansion. When NNMT runs high, the cellular environment favors storage
JAMA 2009;302:977‐84
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D’Andrea FP, Safwat A, Kassem M, Gautier L, Overgaard J, Horsman MR
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