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Drug Metabolism | Basicmedical Key
To facilitate the use of recombinant enzymes to test the substrate specificity in vitro , protein arginine N-methyltransferase (PRMT) was cloned in frame into pGEX vectors using standard molecular biology techniques
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Activated NF-κB promotes the transcriptional upregulation of pro-inflammatory cytokines, including TNF-α, IL-1β, and IL-6 [51, 52]
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