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Frontiers | Preclinical research and potential clinical application of traditional Chinese medicine in cancer treatment: take Astragalus and Dioscorea opposita as an example

Also, hindering pro-inflammatory pathways triggered by Toll-like receptor-LPS (TLR-LPS) and prohibiting Toll-like-receptor-4 (TLR4) activation (28, 29), decreasing inflammatory cytokine production and consequently reducing hepatic triglyceride synthesis through attenuating insulin resistance (29), are reported as potential mechanisms

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Pregnancy is the only sex-specific hard line: because both peptides have ~7-day half-lives, meaningful drug exposure persists for 5–6 weeks after the last injection