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Frontiers | Research progress of glutathione peroxidase family (GPX) in redoxidation
Rat hippocampal slice experiments showed that low μM H 2 O 2 modulated synaptic plasticity by shifting the long-term potentiation (LTP)/long-term depression (LTD) threshold, while higher concentrations of H 2 O 2 suppressed transmission, demonstrating concentration-dependent regulation of neural function [247]
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Work by Reniere et al and others found that PrfA activity is allosterically controlled by the binding of the low molecular weight thiol glutathione (GSH) (6, 7)
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