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In clinical trial settings, Phase II studies (referenced via DOI 10.1210/jcem.83.2.4551) have examined MK-677 in the context of GH deficiency and muscle-wasting conditions, with particular interest in its IGF-1 normalizing effects in older populations
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Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals with an elevated plasma homocysteine concentration: B-PROOF, a randomized controlled trial
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