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We and others have shown that short-term glucose stimulation, which increases prooxidant status via cytoplasmic NOX4, is necessary for efficient insulin secretion, whereas long-term stimulation, which tends to induce oxidative stress, can lead to the development of T2D ( The most important, but still technically elusive problem in redox signaling is the compartmentalization of redox status

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Size:40 days pack

An overview of animal models for investigating the pathogenesis and therapeutic strategies in acute hepatic failure