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While various glutamine-derived amino acids contribute to cancer cell survival, recent studies have shown that aspartate biosynthesis, which can depend on both glutamine flux through the TCA cycle and glutamate transamination 84, 85 , is especially critical due its key role in both purine and pyrimidine biosynthesis to support cell division 84–86 , as discussed in greater detail below

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Introduction Human growth hormone, also referred to as somatotropin, is a protein produced by the anterior pituitary gland