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Conversely, conditional deletion of Smad4 in podocytes attenuated DKD in diabetic eNOS-deficient mice [62], and global Smad3 loss also protected from podocyte injury caused by high fat diet-induced obesity in mice [63], further corroborating the importance of podocyte TGF-β signaling in promoting diabetic glomerulopathy
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See also [edit] References [edit] ↑ Spires et al
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