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That said, you may be a potential candidate if: You've been dealing with chronic knee pain from arthritis, an old injury, or general wear and tear You've tried conservative treatments (physical therapy, medication, injections) without lasting relief You're hoping to explore options before committing to knee replacement surgery You're in reasonably good general health and don't have an active infection, certain autoimmune conditions, or other contraindications You understand this is a regenerative approach — not a guaranteed cure — and want to discuss realistic expectations with a provider You may not be an ideal candidate if you have certain active infections, uncontrolled autoimmune disease, active cancer, or other conditions your provider determines make the procedure unsuitable